STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CEK12652.1PFAM: Nitrogen regulatory protein P-II; JGI identifier:CP488_00134; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
CEK19250.1
PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter; JGI identifier:CP488_02460.
 
 0.991
CEK14241.1
PFAM: Ammonium Transporter Family; TIGRFAM: ammonium transporter; JGI identifier:CP488_00773.
 
 
 0.987
glnD
UTP--GlnB (protein PII) uridylyltransferase, GlnD; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
 
 0.959
CEK12707.1
PFAM: Nitrogen regulatory protein P-II; JGI identifier:CP488_00161.
  
  
 
0.904
CEK19243.1
PFAM: Nitrogen regulatory protein P-II; JGI identifier:CP488_02458; Belongs to the P(II) protein family.
  
  
 
0.903
argB
N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
    
 
 0.766
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
       0.746
CEK12654.1
(R)-citramalate synthase; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; JGI identifier:CP488_00135; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 0.599
CEK19196.1
PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II; JGI identifier:CP488_02439.
  
  
 0.516
CEK12656.1
PFAM: RadC-like JAB domain; TIGRFAM: DNA repair protein radc; JGI identifier:CP488_00136; Belongs to the UPF0758 family.
     
 0.497
Your Current Organism:
Chthonomonas calidirosea
NCBI taxonomy Id: 454171
Other names: C. calidirosea, Chthonomonas calidirosea Lee et al. 2011, DSM 23976, ICMP 18418, strain T49
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.