node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEK12919.1 | CEK14075.1 | CP488_00268 | CP488_00716 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; JGI identifier:CP488_00268. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.928 |
CEK12919.1 | CEK14144.1 | CP488_00268 | CP488_00739 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; JGI identifier:CP488_00268. | PFAM: Homocysteine S-methyltransferase; JGI identifier:CP488_00739. | 0.941 |
CEK12919.1 | CEK14398.1 | CP488_00268 | CP488_00825 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; JGI identifier:CP488_00268. | PFAM: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form; JGI identifier:CP488_00825; Belongs to the methylenetetrahydrofolate reductase family. | 0.629 |
CEK12919.1 | CEK14629.1 | CP488_00268 | CP488_00900 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; JGI identifier:CP488_00268. | ABC-type metal ion transport system, ATPase component; PFAM: NIL domain; JGI identifier:CP488_00900. | 0.907 |
CEK12919.1 | CEK19219.1 | CP488_00268 | CP488_02448 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; JGI identifier:CP488_00268. | ABC-type metal ion transport system, ATPase component; PFAM: NIL domain; JGI identifier:CP488_02448. | 0.907 |
CEK12919.1 | ahcY | CP488_00268 | CP488_02189 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; JGI identifier:CP488_00268. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.816 |
CEK12919.1 | asd | CP488_00268 | CP488_01622 | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; JGI identifier:CP488_00268. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.966 |
CEK14075.1 | CEK12919.1 | CP488_00716 | CP488_00268 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; JGI identifier:CP488_00268. | 0.928 |
CEK14075.1 | CEK14144.1 | CP488_00716 | CP488_00739 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Homocysteine S-methyltransferase; JGI identifier:CP488_00739. | 0.980 |
CEK14075.1 | CEK14398.1 | CP488_00716 | CP488_00825 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form; JGI identifier:CP488_00825; Belongs to the methylenetetrahydrofolate reductase family. | 0.998 |
CEK14075.1 | CEK14629.1 | CP488_00716 | CP488_00900 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ABC-type metal ion transport system, ATPase component; PFAM: NIL domain; JGI identifier:CP488_00900. | 0.926 |
CEK14075.1 | CEK14896.1 | CP488_00716 | CP488_00985 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthase; JGI identifier:CP488_00985. | 0.885 |
CEK14075.1 | CEK18966.1 | CP488_00716 | CP488_02360 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: 56kDa selenium binding protein (SBP56); JGI identifier:CP488_02360. | 0.817 |
CEK14075.1 | CEK19219.1 | CP488_00716 | CP488_02448 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | ABC-type metal ion transport system, ATPase component; PFAM: NIL domain; JGI identifier:CP488_02448. | 0.926 |
CEK14075.1 | ahcY | CP488_00716 | CP488_02189 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.947 |
CEK14075.1 | asd | CP488_00716 | CP488_01622 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.488 |
CEK14144.1 | CEK12919.1 | CP488_00739 | CP488_00268 | PFAM: Homocysteine S-methyltransferase; JGI identifier:CP488_00739. | PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain; JGI identifier:CP488_00268. | 0.941 |
CEK14144.1 | CEK14075.1 | CP488_00739 | CP488_00716 | PFAM: Homocysteine S-methyltransferase; JGI identifier:CP488_00739. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.980 |
CEK14144.1 | CEK14398.1 | CP488_00739 | CP488_00825 | PFAM: Homocysteine S-methyltransferase; JGI identifier:CP488_00739. | PFAM: Methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase, prokaryotic form; JGI identifier:CP488_00825; Belongs to the methylenetetrahydrofolate reductase family. | 0.998 |
CEK14144.1 | CEK14629.1 | CP488_00739 | CP488_00900 | PFAM: Homocysteine S-methyltransferase; JGI identifier:CP488_00739. | ABC-type metal ion transport system, ATPase component; PFAM: NIL domain; JGI identifier:CP488_00900. | 0.926 |