STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CEK14931.1Molecular chaperone (small heat shock protein); PFAM: Hsp20/alpha crystallin family; JGI identifier:CP488_00997; Belongs to the small heat shock protein (HSP20) family. (146 aa)    
Predicted Functional Partners:
CEK16809.1
Molecular chaperone (small heat shock protein); PFAM: Hsp20/alpha crystallin family; JGI identifier:CP488_01634; Belongs to the small heat shock protein (HSP20) family.
  
     0.774
lon
ATP-dependent proteinase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
  
  
 0.739
CEK12415.1
ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); JGI identifier:CP488_00012; Belongs to the ClpA/ClpB family.
  
 
 0.619
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.619
CEK16187.1
ATPase with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); JGI identifier:CP488_01422; Belongs to the ClpA/ClpB family.
  
 
 0.619
CEK16190.1
PFAM: Clp amino terminal domain; JGI identifier:CP488_01423.
  
 
 0.619
CEK19726.1
ATPase with chaperone activity, ATP-binding subunit; PFAM: ATPase family associated with various cellular activities (AAA); JGI identifier:CP488_02618; Belongs to the ClpA/ClpB family.
  
 
 0.619
grpE
Molecular chaperone GrpE (heat shock protein); Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. [...]
 
  
 0.595
CEK16482.1
Predicted transcriptional regulator; PFAM: Helix-turn-helix domain; JGI identifier:CP488_01522.
  
 
 0.592
CEK13321.1
Molecular chaperone; PFAM: Hsp70 protein; JGI identifier:CP488_00460.
  
 
 0.529
Your Current Organism:
Chthonomonas calidirosea
NCBI taxonomy Id: 454171
Other names: C. calidirosea, Chthonomonas calidirosea Lee et al. 2011, DSM 23976, ICMP 18418, strain T49
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