STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhBRNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (213 aa)    
Predicted Functional Partners:
CEK16986.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.904
CEK16160.1
PFAM: Peptidase S24-like; Signal peptidase, peptidase S26; TIGRFAM: signal peptidase I, bacterial type; JGI identifier:CP488_01413; Belongs to the peptidase S26 family.
  
    0.899
trmD
tRNA (Guanine37-N(1)-) methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
 
  
 0.896
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
   
 0.874
CEK17481.1
PFAM: Lipid-A-disaccharide synthetase; JGI identifier:CP488_01866; Belongs to the LpxB family.
 
  
 0.852
CEK16153.1
PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein; JGI identifier:CP488_01411; Belongs to the UPF0102 family.
       0.798
CEK16246.1
Ribonuclease HI; PFAM: Reverse transcriptase-like; JGI identifier:CP488_01443.
   
 
 0.784
rimM
16S rRNA processing protein RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family.
 
    0.777
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
 
 0.745
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 
 0.721
Your Current Organism:
Chthonomonas calidirosea
NCBI taxonomy Id: 454171
Other names: C. calidirosea, Chthonomonas calidirosea Lee et al. 2011, DSM 23976, ICMP 18418, strain T49
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