STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDM64160.1PFAM: NADH:flavin oxidoreductase / NADH oxidase family. (354 aa)    
Predicted Functional Partners:
CDM66086.1
PFAM: Electron transfer flavoprotein domain.
  
 
 0.800
CDM67034.1
Glutamate synthase (NADH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
    
 0.789
CDM67091.1
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
 
    0.720
CDM66087.1
PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain.
   
 
 0.685
CDM64159.1
Zn-dependent oxidoreductase, NADPH:quinone reductase; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase.
 
  
 0.665
CDM64373.1
NAD(P)H-nitrite reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Reductase C-terminal; Rieske [2Fe-2S] domain.
    
 0.647
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.621
CDM66926.1
NADPH-dependent glutamate synthase beta chain-like oxidoreductase; PFAM: Oxidoreductase NAD-binding domain.
  
 
 0.612
CDM64746.1
NAD(FAD)-dependent dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
   
 
 0.596
CDM65857.1
Predicted flavoprotein; PFAM: NADPH-dependent FMN reductase.
    
 0.589
Your Current Organism:
Pyrinomonas methylaliphatogenes
NCBI taxonomy Id: 454194
Other names: Acidobacteriaceae bacterium K22, DSM 25857, ICMP 18710, P. methylaliphatogenes, Pyrinomonas methylaliphatogenes Crowe et al. 2014, strain K22
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