STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panBKetopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (302 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 0.999
panD
L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
  
 0.963
CDM67001.1
Hypothetical protein; PFAM: Domain of unknown function (DUF2520); Rossmann-like domain.
 
  
  0.843
rsmI
Probable S-adenosylmethionine-dependent methyltransferase, YraL family; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
      0.742
CDM64300.1
PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase.
  
 
 0.738
CDM64664.1
Nicotinate-nucleotide pyrophosphorylase (carboxylating); PFAM: Quinolinate phosphoribosyl transferase, C-terminal domain; Quinolinate phosphoribosyl transferase, N-terminal domain; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family.
      0.685
CDM64500.1
Aminodeoxychorismate synthase, component I; PFAM: Aminotransferase class IV; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade.
 
  
 0.678
ilvD
PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
     
 0.640
ilvE
Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
 0.591
CDM64297.1
Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS-like protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; TIGRFAM: 4-hydroxybenzoyl-CoA reductase, gamma subunit.
       0.561
Your Current Organism:
Pyrinomonas methylaliphatogenes
NCBI taxonomy Id: 454194
Other names: Acidobacteriaceae bacterium K22, DSM 25857, ICMP 18710, P. methylaliphatogenes, Pyrinomonas methylaliphatogenes Crowe et al. 2014, strain K22
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