STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDM64442.1Peroxiredoxin; PFAM: AhpC/TSA family. (198 aa)    
Predicted Functional Partners:
CDM64046.1
Thiol-disulfide isomerase-like thioredoxin; PFAM: Redoxin.
  
     0.774
CDM66672.1
Peroxiredoxin; PFAM: Redoxin.
  
     0.774
CDM67103.1
Thiol-disulfide isomerase-like thioredoxin; PFAM: AhpC/TSA family.
  
     0.774
CDM64676.1
Thiol-disulfide isomerase-like thioredoxin; PFAM: AhpC/TSA family.
  
     0.773
CDM64441.1
PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-ubiquinone oxidoreductase chain 4, amino terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M.
       0.645
CDM64045.1
PFAM: AhpC/TSA family.
  
     0.628
CDM65295.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.625
CDM66472.1
Cobalamin-dependent methionine synthase I; PFAM: Methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase.
    
  0.625
nuoN
Proton-translocating NADH-quinone oxidoreductase, chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
       0.457
CDM64440.1
PFAM: NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus; NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L.
  
    0.449
Your Current Organism:
Pyrinomonas methylaliphatogenes
NCBI taxonomy Id: 454194
Other names: Acidobacteriaceae bacterium K22, DSM 25857, ICMP 18710, P. methylaliphatogenes, Pyrinomonas methylaliphatogenes Crowe et al. 2014, strain K22
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