STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDM65512.1CRISPR-associated helicase Cas3, subtype Dpsyc; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit; TIGRFAM: CRISPR-associated helicase Cas3, subtype Dpsyc. (895 aa)    
Predicted Functional Partners:
CDM65513.1
TIGRFAM: CRISPR-associated protein GSU0052/csb3, Dpsyc system.
 
    0.950
cas1
CRISPR-associated protein, Cas1 family/CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.920
cas2
CRISPR-associated protein, Cas2 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.835
CDM65514.1
CRISPR-associated protein, Csx4 family; PFAM: CRISPR-associated protein GSU0053 (Cas_GSU0053); TIGRFAM: CRISPR-associated protein GSU0053/csb1, Dpsyc system.
  
    0.770
CDM65515.1
CRISPR-associated protein GSU0054/csb2, Dpsyc system; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054); TIGRFAM: CRISPR-associated protein GSU0054/csb2, Dpsyc system.
  
    0.759
CDM65517.1
TIGRFAM: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE.
  
  
 0.613
CDM65516.1
CRISPR-associated protein GSU0054/csb2, Dpsyc system; PFAM: CRISPR-associated protein, GSU0054 family (Cas_GSU0054); TIGRFAM: CRISPR-associated protein GSU0054/csb2, Dpsyc system.
  
    0.601
CDM65519.1
PFAM: RAMP superfamily; TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm3.
     
 0.601
CDM65518.1
PFAM: Protein of unknown function (DUF310); TIGRFAM: CRISPR type III-A/MTUBE-associated protein Csm2.
       0.600
CDM65520.1
Hypothetical protein; TIGRFAM: CRISPR type III-A/MTUBE-associated RAMP protein Csm4.
       0.581
Your Current Organism:
Pyrinomonas methylaliphatogenes
NCBI taxonomy Id: 454194
Other names: Acidobacteriaceae bacterium K22, DSM 25857, ICMP 18710, P. methylaliphatogenes, Pyrinomonas methylaliphatogenes Crowe et al. 2014, strain K22
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