STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDM65670.1Iron-sulfur cluster biosynthesis protein, NifU-like protein; PFAM: NifU-like N terminal domain. (120 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase family protein; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
 0.999
CDM66669.1
Hypothetical protein.
  
 
 0.982
CDM67064.1
Selenocysteine lyase; PFAM: Aminotransferase class-V.
 
 0.944
CDM64969.1
Cysteine desulfurase-like protein, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.
  
 0.927
CDM66522.1
Ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain.
  
 0.814
CDM64967.1
PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC.
  
  
 0.798
CDM64486.1
PFAM: Iron-sulphur cluster biosynthesis; TIGRFAM: Iron-sulfur cluster assembly accessory protein; Belongs to the HesB/IscA family.
  
  
 0.793
CDM64966.1
Iron-regulated ABC transporter membrane component SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB.
  
  
 0.711
CDM64968.1
FeS assembly protein SufD; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufD.
  
  
 0.711
CDM65234.1
Predicted metal-sulfur cluster biosynthetic enzyme; PFAM: Domain of unknown function DUF59.
  
    0.709
Your Current Organism:
Pyrinomonas methylaliphatogenes
NCBI taxonomy Id: 454194
Other names: Acidobacteriaceae bacterium K22, DSM 25857, ICMP 18710, P. methylaliphatogenes, Pyrinomonas methylaliphatogenes Crowe et al. 2014, strain K22
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.