STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipBLipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (222 aa)    
Predicted Functional Partners:
lipA
Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 0.996
CDM64517.1
PFAM: Beta-lactamase superfamily domain.
 
    
 0.910
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
   
 0.889
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.791
CDM66261.1
PFAM: Glycosyl transferase family 2.
    
 0.780
CDM66266.1
PFAM: Glycosyl transferase family 2.
    
 0.780
CDM64723.1
AMP-forming long-chain acyl-CoA synthetase; PFAM: Phosphopantetheine attachment site; Male sterility protein; Acyltransferase; AMP-binding enzyme; AMP-binding enzyme C-terminal domain; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
   
 0.717
CDM66162.1
AMP-forming long-chain acyl-CoA synthetase; PFAM: Phosphopantetheine attachment site; Acyltransferase; AMP-binding enzyme; AMP-binding enzyme C-terminal domain.
   
 0.711
CDM65184.1
PFAM: Glycosyl transferase family 2.
  
 
 0.705
CDM65185.1
PFAM: Glycosyl transferase family 2.
  
 
 0.705
Your Current Organism:
Pyrinomonas methylaliphatogenes
NCBI taxonomy Id: 454194
Other names: Acidobacteriaceae bacterium K22, DSM 25857, ICMP 18710, P. methylaliphatogenes, Pyrinomonas methylaliphatogenes Crowe et al. 2014, strain K22
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.