STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISG_00108Uncharacterized protein. (156 aa)    
Predicted Functional Partners:
CISG_10075
FGGY_C domain-containing protein.
  
 
 0.830
CISG_05058
Uncharacterized protein.
  
 
 0.821
MRI1
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
 
 0.816
ADI1
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
  
 
 0.812
CISG_03367
Glyceraldehyde-3-phosphate dehydrogenase.
     
 0.712
CISG_07591
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
     
 0.705
CISG_01237
Fructose-1,6-bisphosphatase; Belongs to the FBPase class 1 family.
   
 
 0.697
CISG_04684
6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
     
 0.675
CISG_10118
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
     
 0.667
CISG_05040
Phosphorylase family 2 protein.
  
 
 0.662
Your Current Organism:
Coccidioides immitis RMSCC3703
NCBI taxonomy Id: 454286
Other names: C. immitis RMSCC 3703, Coccidioides immitis RMSCC 3703
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.