STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISG_00502Aminotran_1_2 domain-containing protein. (442 aa)    
Predicted Functional Partners:
CISG_01556
Tryptophan synthase.
   
 
 0.905
CISG_00886
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
   
 
 0.885
CISG_03324
Aspartokinase.
   
 
 0.758
CISG_05317
Prephenate dehydrogenase.
    
 0.748
CISG_04311
Chorismate mutase.
     
 0.735
CISG_08036
Homoserine dehydrogenase.
   
 0.731
BNA4
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
   
 
 0.684
BNA5
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family.
   
 
 0.666
CISG_03103
Chorismate synthase.
  
 
 0.650
CISG_03331
Chorismate mutase/prephenate dehydratase.
    
 0.650
Your Current Organism:
Coccidioides immitis RMSCC3703
NCBI taxonomy Id: 454286
Other names: C. immitis RMSCC 3703, Coccidioides immitis RMSCC 3703
Server load: low (18%) [HD]