STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISG_037693-isopropylmalate dehydratase. (304 aa)    
Predicted Functional Partners:
CISG_06261
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.969
CISG_08901
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 0.969
CISG_00365
2-isopropylmalate synthase.
  
 
 0.968
CISG_03048
Acetolactate synthase small subunit.
  
  
 0.959
CISG_06769
Dihydroxy-acid dehydratase.
  
 
 0.954
CISG_06514
Dihydroxy-acid dehydratase.
  
 
 0.954
CISG_01710
Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.939
CISG_08083
Uncharacterized protein.
  
 
 0.939
CISG_09518
Hydroxymethylglutaryl-CoA lyase.
  
 
 0.929
CISG_05132
DUF1752 domain-containing protein.
  
 0.912
Your Current Organism:
Coccidioides immitis RMSCC3703
NCBI taxonomy Id: 454286
Other names: C. immitis RMSCC 3703, Coccidioides immitis RMSCC 3703
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