STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISG_01229Saccharopine dehydrogenase. (401 aa)    
Predicted Functional Partners:
CISG_06036
Spermidine synthase; Belongs to the spermidine/spermine synthase family.
   
 0.962
CISG_05237
Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family.
  
 
 0.938
CISG_02231
3-isopropylmalate dehydrogenase.
   
  
 0.817
CISG_00613
S-adenosylmethionine decarboxylase proenzyme.
     
 0.796
CISG_06319
L-aminoadipate-semialdehyde dehydrogenase.
  
 
 0.793
CISG_06318
Alpha-aminoadipate reductase large subunit.
  
 
 0.793
CISG_04882
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 
 0.735
CISG_08205
Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 
 0.735
CISG_07188
Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
   
  
 0.667
CISG_05167
Agmatinase; Belongs to the arginase family.
    
 0.665
Your Current Organism:
Coccidioides immitis RMSCC3703
NCBI taxonomy Id: 454286
Other names: C. immitis RMSCC 3703, Coccidioides immitis RMSCC 3703
Server load: low (14%) [HD]