STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CISG_01529Propionyl-CoA carboxylase beta chain. (542 aa)    
Predicted Functional Partners:
CISG_00778
Acetyl-/propionyl-coenzyme A carboxylase alpha chain.
 
 0.998
CISG_01528
Biotin carboxylase.
 
 0.891
CISG_01144
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 
 0.887
CISG_06538
Biotin-[acetyl-CoA-carboxylase] ligase.
  
 
 0.879
CISG_05048
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.878
CISG_00305
Short-chain dehydrogenase/reductase SDR.
  
 0.876
CISG_04584
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
  
 
 0.874
CISG_04196
3-hydroxybutyryl-CoA dehydrogenase.
  
 
 0.873
CISG_05099
4-hydroxyphenylpyruvate dioxygenase.
  
 
 0.871
CISG_06351
4-hydroxyphenylpyruvate dioxygenase.
  
 
 0.871
Your Current Organism:
Coccidioides immitis RMSCC3703
NCBI taxonomy Id: 454286
Other names: C. immitis RMSCC 3703, Coccidioides immitis RMSCC 3703
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