Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mrpBNa(+)/H(+) antiporter subunit B. (135 aa)    
Predicted Functional Partners:
nuoL_2
NADH-quinone oxidoreductase chain L.
 
 
 0.998
mrpC
Na(+)/H(+) antiporter subunit C.
 
 
 0.996
mrpE
Na(+)/H(+) antiporter subunit E.
 
 
 0.994
mrpG
Na(+)/H(+) antiporter subunit G.
 
 
 0.994
nuoL_1
NADH-quinone oxidoreductase chain L.
 
 0.993
mrpF
Na(+)/H(+) antiporter subunit F.
 
 
 0.992
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
   0.716
Ljam_1655
NADH-ubiquinone oxidoreductase chain 5.
 
 
 0.663
nuoL_3
NADH-quinone oxidoreductase chain L.
  
 
 0.601
Ljam_0024
Putative sodium/hydrogen exchanger family protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.479
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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