Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ljam_0100Glutamate synthase; Belongs to the glutamate synthase family. (510 aa)    
Predicted Functional Partners:
fadH
2,4-dienoyl-CoA reductase FadH1.
 
 0.996
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.873
Ljam_0503
Polyketide synthase.
     
 0.749
Ljam_1060
Polyketide synthase.
     
 0.749
Ljam_0791
Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.735
Ljam_1066
Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.716
Ljam_2014
Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 0.716
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
 0.715
Ljam_2622
Oxaloacetate decarboxylase subunit alpha.
   
 
 0.701
apc3
Acetophenone carboxylase gamma subunit.
     
  0.690
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
Server load: medium (48%) [HD]