deaD protein (Legionella jamestowniensis) - STRING interaction network

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deaD

ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (556 aa)

Predicted Functional Partners:

recQ

0.886

Ljam_0503

0.861

Ljam_1060

0.861

pnp

0.821

rne

0.779

yjeF

0.764

rplC

0.759

rplD

0.695

fusA

0.682

rrmJ

0.670

Your Current Organism:

Legionella jamestowniensis

NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ljam_0503	Ljam_1060	Ljam_0503	Ljam_1060	Polyketide synthase.	Polyketide synthase.	0.999
Ljam_0503	deaD	Ljam_0503	Ljam_0145	Polyketide synthase.	ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	0.861
Ljam_0503	fusA	Ljam_0503	Ljam_0213	Polyketide synthase.	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.604
Ljam_0503	recQ	Ljam_0503	Ljam_0913	Polyketide synthase.	ATP-dependent DNA helicase RecQ.	0.516
Ljam_0503	rplC	Ljam_0503	Ljam_2165	Polyketide synthase.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.945
Ljam_0503	rplD	Ljam_0503	Ljam_2166	Polyketide synthase.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.935
Ljam_0503	yjeF	Ljam_0503	Ljam_0268	Polyketide synthase.	Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]	0.624
Ljam_1060	Ljam_0503	Ljam_1060	Ljam_0503	Polyketide synthase.	Polyketide synthase.	0.999
Ljam_1060	deaD	Ljam_1060	Ljam_0145	Polyketide synthase.	ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	0.861
Ljam_1060	fusA	Ljam_1060	Ljam_0213	Polyketide synthase.	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.604
Ljam_1060	recQ	Ljam_1060	Ljam_0913	Polyketide synthase.	ATP-dependent DNA helicase RecQ.	0.516
Ljam_1060	rplC	Ljam_1060	Ljam_2165	Polyketide synthase.	50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.945
Ljam_1060	rplD	Ljam_1060	Ljam_2166	Polyketide synthase.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.935
Ljam_1060	yjeF	Ljam_1060	Ljam_0268	Polyketide synthase.	Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]	0.624
deaD	Ljam_0503	Ljam_0145	Ljam_0503	ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	Polyketide synthase.	0.861
deaD	Ljam_1060	Ljam_0145	Ljam_1060	ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	Polyketide synthase.	0.861
deaD	fusA	Ljam_0145	Ljam_0213	ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.682
deaD	pnp	Ljam_0145	Ljam_1660	ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	Polynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.	0.821
deaD	recQ	Ljam_0145	Ljam_0913	ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	ATP-dependent DNA helicase RecQ.	0.886
deaD	rne	Ljam_0145	Ljam_2793	ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.	Ribonuclease E.	0.779

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