| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ljam_0181 | Ljam_0182 | Ljam_0181 | Ljam_0182 | Putative amino acid ABC transporter, periplasmic binding protein. | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | 0.538 |
| Ljam_0181 | Ljam_0183 | Ljam_0181 | Ljam_0183 | Putative amino acid ABC transporter, periplasmic binding protein. | Sensory box histidine kinase/response regulator. | 0.775 |
| Ljam_0181 | Ljam_0431 | Ljam_0181 | Ljam_0431 | Putative amino acid ABC transporter, periplasmic binding protein. | Sensory box histidine kinase/response regulator. | 0.775 |
| Ljam_0181 | Ljam_1150 | Ljam_0181 | Ljam_1150 | Putative amino acid ABC transporter, periplasmic binding protein. | Sensory box histidine kinase/response regulator. | 0.775 |
| Ljam_0181 | Ljam_1227 | Ljam_0181 | Ljam_1227 | Putative amino acid ABC transporter, periplasmic binding protein. | Sensory box histidine kinase/response regulator. | 0.775 |
| Ljam_0182 | Ljam_0181 | Ljam_0182 | Ljam_0181 | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | Putative amino acid ABC transporter, periplasmic binding protein. | 0.538 |
| Ljam_0182 | Ljam_0183 | Ljam_0182 | Ljam_0183 | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | Sensory box histidine kinase/response regulator. | 0.635 |
| Ljam_0182 | Ljam_0431 | Ljam_0182 | Ljam_0431 | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | Sensory box histidine kinase/response regulator. | 0.635 |
| Ljam_0182 | Ljam_1150 | Ljam_0182 | Ljam_1150 | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | Sensory box histidine kinase/response regulator. | 0.635 |
| Ljam_0182 | Ljam_1227 | Ljam_0182 | Ljam_1227 | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | Sensory box histidine kinase/response regulator. | 0.635 |
| Ljam_0182 | Ljam_1768 | Ljam_0182 | Ljam_1768 | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | Bacterioferritin comigratory protein. | 0.473 |
| Ljam_0182 | glnA | Ljam_0182 | Ljam_0843 | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | Glutamine synthetase. | 0.771 |
| Ljam_0182 | glnD | Ljam_0182 | Ljam_2313 | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | protein-PII uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.890 |
| Ljam_0182 | glnK | Ljam_0182 | Ljam_0106 | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | Carbamoylphosphate synthase large subunit; Belongs to the P(II) protein family. | 0.540 |
| Ljam_0182 | nadE | Ljam_0182 | Ljam_1041 | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | Glutamine dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.529 |
| Ljam_0183 | Ljam_0181 | Ljam_0183 | Ljam_0181 | Sensory box histidine kinase/response regulator. | Putative amino acid ABC transporter, periplasmic binding protein. | 0.775 |
| Ljam_0183 | Ljam_0182 | Ljam_0183 | Ljam_0182 | Sensory box histidine kinase/response regulator. | Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | 0.635 |
| Ljam_0183 | Ljam_0431 | Ljam_0183 | Ljam_0431 | Sensory box histidine kinase/response regulator. | Sensory box histidine kinase/response regulator. | 0.999 |
| Ljam_0183 | Ljam_1150 | Ljam_0183 | Ljam_1150 | Sensory box histidine kinase/response regulator. | Sensory box histidine kinase/response regulator. | 0.999 |
| Ljam_0183 | Ljam_1227 | Ljam_0183 | Ljam_1227 | Sensory box histidine kinase/response regulator. | Sensory box histidine kinase/response regulator. | 0.999 |
