STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mvaAHydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family. (432 aa)    
Predicted Functional Partners:
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
   
 0.961
Ljam_0227
Mevalonate kinase.
 
 0.933
Ljam_0226
Mevalonate diphosphate decarboxylase.
 
 
 0.919
Ljam_0214
Hypothetical protein.
  
 0.874
Ljam_0217
Fusaric acid resistance protein family protein.
       0.633
Ljam_0218
Hypothetical protein.
       0.633
hmgcll
Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.
    
  0.555
Ljam_0503
Polyketide synthase.
     
 0.517
Ljam_1060
Polyketide synthase.
     
 0.517
Ljam_0219
ABC transporter permease.
       0.501
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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