Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
icmXIntracellular multiplication protein IcmX. (480 aa)    
Predicted Functional Partners:
icmW
Intracellular multiplication protein IcmW.
     
 0.945
Ljam_0251
DotA.
   
   0.941
Ljam_0125
Protein IcmE (DotG).
    
 
 0.934
icmV
Intracellular multiplication protein IcmV.
     
 0.893
dotF
Component of the Dot/Icm secretion system.
    
 
 0.837
Ljam_0124
IcmK protein.
    
 
 0.813
icmS
Protein IcmS.
      
 0.609
icmQ
IcmQ protein.
      
 0.609
icmP
IcmP protein.
      
 0.609
Ljam_0132
IcmF.
      
 0.609
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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