| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ljam_0724 | glyA | Ljam_0724 | Ljam_0174 | Cysteine synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.874 |
| Ljam_0724 | trpA | Ljam_0724 | Ljam_0565 | Cysteine synthase. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.856 |
| Ljam_0724 | trpB | Ljam_0724 | Ljam_0564 | Cysteine synthase. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.896 |
| Ljam_0724 | trpC | Ljam_0724 | Ljam_1298 | Cysteine synthase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.630 |
| Ljam_0724 | trpE | Ljam_0724 | Ljam_2294 | Cysteine synthase. | Anthranilate synthase. | 0.403 |
| Ljam_0724 | trpF | Ljam_0724 | Ljam_0563 | Cysteine synthase. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.557 |
| glyA | Ljam_0724 | Ljam_0174 | Ljam_0724 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cysteine synthase. | 0.874 |
| glyA | trpA | Ljam_0174 | Ljam_0565 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.869 |
| glyA | trpB | Ljam_0174 | Ljam_0564 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.869 |
| glyA | trpC | Ljam_0174 | Ljam_1298 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.462 |
| glyA | trpE | Ljam_0174 | Ljam_2294 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Anthranilate synthase. | 0.611 |
| glyA | trpF | Ljam_0174 | Ljam_0563 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.541 |
| lgt | trpA | Ljam_2045 | Ljam_0565 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.914 |
| lgt | trpB | Ljam_2045 | Ljam_0564 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.896 |
| pabB | trpA | Ljam_2366 | Ljam_0565 | Para-aminobenzoate synthase, component I. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.965 |
| pabB | trpB | Ljam_2366 | Ljam_0564 | Para-aminobenzoate synthase, component I. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.974 |
| pabB | trpC | Ljam_2366 | Ljam_1298 | Para-aminobenzoate synthase, component I. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.997 |
| pabB | trpD | Ljam_2366 | Ljam_1297 | Para-aminobenzoate synthase, component I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.997 |
| pabB | trpE | Ljam_2366 | Ljam_2294 | Para-aminobenzoate synthase, component I. | Anthranilate synthase. | 0.986 |
| pabB | trpF | Ljam_2366 | Ljam_0563 | Para-aminobenzoate synthase, component I. | N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. | 0.949 |
