Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ljam_1154Short chain dehydrogenase/reductase family oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (239 aa)    
Predicted Functional Partners:
Ljam_0503
Polyketide synthase.
  
 
 0.939
Ljam_1060
Polyketide synthase.
  
 
 0.939
Ljam_1460
Polyketide synthase.
  
 
 0.809
Ljam_1459
Non-ribosomal peptide synthetase/polyketide synthetase.
  
 
 0.787
Ljam_2195
3-oxoacyl-ACP reductase.
  
  
  0.686
fabG_1
3-oxoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
  0.676
Ljam_1201
Short chain dehydrogenase/reductase family transporter protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
  0.658
Ljam_0432
Peptide synthetase, non-ribosomal; Belongs to the ATP-dependent AMP-binding enzyme family.
   
  0.616
Ljam_2055
Pteridine reductase.
  
  
  0.569
Ljam_1149
Peptide synthetase, non-ribosomal; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
  0.533
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.