STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pilAType IV pilus assembly protein PilA; Belongs to the N-Me-Phe pilin family. (135 aa)    
Predicted Functional Partners:
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
   
 0.812
pilE
Type-IV pilin.
 
  
 0.742
bolA
Regulator of penicillin binding proteins and beta lactamase transcription (morphogene); Belongs to the BolA/IbaG family.
       0.639
Ljam_1250
Hypothetical protein.
       0.621
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
      
 0.609
pilM
Tfp pilus assembly protein, ATPase PilM.
 
   
 0.540
Ljam_2419
Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
   
 0.508
pilN
Tfp pilus assembly protein PilN.
  
   
 0.505
Ljam_0846
General secretion pathway protein LspH.
 
 
 0.491
pilB
Pilus assembly protein PilB.
 
  
 0.452
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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