| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ljam_0724 | glyA | Ljam_0724 | Ljam_0174 | Cysteine synthase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.874 |
| Ljam_0724 | ltaE | Ljam_0724 | Ljam_1570 | Cysteine synthase. | Low specificity L-threonine aldolase. | 0.875 |
| Ljam_0724 | tdh | Ljam_0724 | Ljam_2868 | Cysteine synthase. | Threonine(-3-)dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.841 |
| Ljam_1571 | Ljam_1572 | Ljam_1571 | Ljam_1572 | Putative aminoglycoside phosphotransferase. | Transmembrane protein. | 0.807 |
| Ljam_1571 | ltaE | Ljam_1571 | Ljam_1570 | Putative aminoglycoside phosphotransferase. | Low specificity L-threonine aldolase. | 0.866 |
| Ljam_1572 | Ljam_1571 | Ljam_1572 | Ljam_1571 | Transmembrane protein. | Putative aminoglycoside phosphotransferase. | 0.807 |
| Ljam_1572 | ltaE | Ljam_1572 | Ljam_1570 | Transmembrane protein. | Low specificity L-threonine aldolase. | 0.807 |
| fadH | gcsA | Ljam_0139 | Ljam_2075 | 2,4-dienoyl-CoA reductase FadH1. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.657 |
| fadH | gcsB | Ljam_0139 | Ljam_2073 | 2,4-dienoyl-CoA reductase FadH1. | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.657 |
| fadH | glyA | Ljam_0139 | Ljam_0174 | 2,4-dienoyl-CoA reductase FadH1. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.708 |
| fadH | kbl | Ljam_0139 | Ljam_2867 | 2,4-dienoyl-CoA reductase FadH1. | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.464 |
| fadH | ltaE | Ljam_0139 | Ljam_1570 | 2,4-dienoyl-CoA reductase FadH1. | Low specificity L-threonine aldolase. | 0.727 |
| gcsA | fadH | Ljam_2075 | Ljam_0139 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 2,4-dienoyl-CoA reductase FadH1. | 0.657 |
| gcsA | gcsB | Ljam_2075 | Ljam_2073 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 0.999 |
| gcsA | glyA | Ljam_2075 | Ljam_0174 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.932 |
| gcsA | kbl | Ljam_2075 | Ljam_2867 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.841 |
| gcsA | ltaE | Ljam_2075 | Ljam_1570 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Low specificity L-threonine aldolase. | 0.868 |
| gcsA | ydfG | Ljam_2075 | Ljam_2477 | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | NADP-dependent L-serine/L-allo-threonine dehydrogenase ydfG; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.460 |
| gcsB | fadH | Ljam_2073 | Ljam_0139 | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | 2,4-dienoyl-CoA reductase FadH1. | 0.657 |
| gcsB | gcsA | Ljam_2073 | Ljam_2075 | Glycine dehydrogenase subunit 2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. C-terminal subunit subfamily. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
