STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsBAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (621 aa)    
Predicted Functional Partners:
yfcX
Enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.938
fadB
3-hydroxyacyl CoA dehydrogenase oxidoreductase protein.
  
 
 0.938
Ljam_0503
Polyketide synthase.
  
 0.937
Ljam_1060
Polyketide synthase.
  
 0.937
pta_1
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.923
pta_2
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
 
 0.923
Ljam_2128
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
  
 
  0.914
Ljam_2127
Methylmalonate-semialdehyde dehydrogenase.
  
 0.909
Ljam_2400
Phosphate acetyl/butaryl transferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.899
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
 
 0.837
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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