Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tpm-2Thiopurine S-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family. (221 aa)    
Predicted Functional Partners:
Ljam_1575
Coenzyme Q (ubiquinone) biosynthesis protein Coq4.
  
 
 0.648
moaC
Cyclic pyranopterin monophosphate synthase accessory protein.
       0.623
mog
Molybdopterin adenylyltransferase.
       0.623
Ljam_2390
Hypothetical protein.
       0.566
Ljam_1786
Hypothetical protein.
  
 
 0.542
arp_4
Ankyrin repeat protein.
 
 
   0.522
queF
GTP cyclohydrolase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
   
 
 0.499
Ljam_0503
Polyketide synthase.
  
 
 0.495
Ljam_1060
Polyketide synthase.
  
 
 0.495
Ljam_0523
Hypothetical protein.
   
 0.477
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.