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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
ala_2D-alanine-aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (298 aa)    
Predicted Functional Partners:
Ljam_0724
Cysteine synthase.
  
 0.917
Ljam_1547
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 0.891
Ljam_1066
Glu/Leu/Phe/Val dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.878
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
     
 0.877
pdhA
Pyruvate dehydrogenase e1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
     
 0.872
odpB
Pyruvate dehydrogenase E1 subunit beta.
   
 0.862
edd
6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
  
 0.859
gshA
Glutamate--cysteine ligase.
     
  0.834
hmgcll
Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.
  
 0.827
pheA
P-protein.
 
  
 0.762
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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