STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ala_2D-alanine-aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (298 aa)    
Predicted Functional Partners:
edd
6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
  
 0.913
hmgcll
Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2.
  
 0.873
pheA
P-protein.
 
  
 0.851
trpE
Anthranilate synthase.
  
 
 0.837
Ljam_0503
Polyketide synthase.
  
 
 0.828
Ljam_1060
Polyketide synthase.
  
 
 0.828
Ljam_1547
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
  
 0.818
Ljam_1149
Peptide synthetase, non-ribosomal; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.811
Ljam_1456
Peptide synthetase, non-ribosomal.
  
 0.811
lysAC_2
Diaminopimelate decarboxylase, aspartate kinase (fusion of lysA and lysC); Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.797
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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