Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Ljam_2448Hypothetical protein. (267 aa)    
Predicted Functional Partners:
Ljam_2446
Hypothetical protein.
 
     0.907
Ljam_2447
Aminotransferase.
       0.866
recJ
single-stranded-DNA-specific exonuclease RecJ.
       0.866
yjbN
tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
       0.768
Ljam_1607
Putative membrane protein YdgA-like protein.
  
     0.739
Ljam_0263
Zinc-finger domain protein.
  
     0.702
Ljam_1484
Protein LvrA.
  
     0.619
secA
Preprotein translocase, secretion protein SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
       0.611
mutT
Mutator protein MutT; Belongs to the Nudix hydrolase family.
       0.609
Ljam_1411
Transmembrane protein.
  
     0.600
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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