Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ljam_2462Rtn protein. (521 aa)    
Predicted Functional Partners:
Ljam_1834
Sensor histidine kinase.
 
 
 0.951
Ljam_1850
Regulatory protein (GGDEF, PAS, PAC domains).
 
 0.941
pleD
Sensor histidine kinase.
 0.922
Ljam_0330
Two component response regulator with GGDEF domain protein.
 
 
 0.891
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.866
Ljam_2461
Hypothetical protein.
       0.866
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
       0.866
Ljam_1027
GGDEF domain-containing protein.
  
 
  0.856
Ljam_0718
GGDEF domain-containing protein.
  
 
  0.855
Ljam_1741
Regulatory protein (GGDEF and EAL domains).
 
0.829
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.