Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gorGlutathione reductase. (449 aa)    
Predicted Functional Partners:
Ljam_1547
2-oxoisovalerate dehydrogenase, E1 component, alpha and beta fusion.
 
 0.973
btuE
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.933
gshB
Glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
     
 0.901
Ljam_1602
Gamma-glutamyltranspeptidase.
     
 0.877
Ljam_2483
Transferase.
       0.866
gst
Glutathione S-transferase; Belongs to the GST superfamily.
   
 0.863
odpB
Pyruvate dehydrogenase E1 subunit beta.
 
 0.795
sucA
2-oxoglutarate dehydrogenase E1.
  
 0.773
aceF
Pyruvate dehydrogenase (dihydrolipoyltransacetylase component) E2p; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
  0.768
sucB
Dihydrolipoamide succinyltransferase subunit E2; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
  0.749
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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