STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ljam_2693Maf-like protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (202 aa)    
Predicted Functional Partners:
Ljam_2694
Zip family transporter.
       0.802
Ljam_2695
2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.793
tusA
Sulfurtransferase TusA; Belongs to the sulfur carrier protein TusA family.
  
    0.785
Ljam_2698
tRNA-specific 2-thiouridylase MnmA.
  
    0.785
Ljam_2696
Cation efflux family protein; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
  
    0.784
radC
DNA repair protein RadC; Belongs to the UPF0758 family.
 
  
 0.774
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
    
 0.610
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.478
hisI
Histidine biosynthesis bifunctional protein hisIE (Phosphoribosyl-AMP cyclohydrolase/Phosphoribosyl-ATP pyrophosphatase); In the N-terminal section; belongs to the PRA-CH family.
      
 0.418
Ljam_2692
Ubiquitin conjugation factor E4 family domain protein (U-box).
       0.406
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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