STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ljam_2740Serine metalloprotease; Belongs to the peptidase S8 family. (559 aa)    
Predicted Functional Partners:
Ljam_1444
Regulator of chromosome condensation (RCC1) repeat protein.
   
 0.873
Ljam_1886
Regulator of chromosome condensation (RCC1) repeat protein.
   
 0.873
Ljam_0088
SURF1 family protein.
  
 
   0.805
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 
 0.782
Ljam_1709
Aminopeptidase.
  
  
 0.770
legL6
Leucine-rich repeat-containing protein.
   
 0.733
rtxA-1
Structural toxin protein RtxA.
  
 
 0.718
Ljam_1033
Trypsin.
 
  
 0.637
Ljam_0503
Polyketide synthase.
  
 
 0.633
Ljam_1060
Polyketide synthase.
  
 
 0.633
Your Current Organism:
Legionella jamestowniensis
NCBI taxonomy Id: 455
Other names: ATCC 35298, CCUG 29669, CIP 103845, DSM 19215, JCM 7590, L. jamestowniensis, Legionella jamestownensis, NCTC 11981, strain JA-26-G1-E2
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