Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A368PIX1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (347 aa)    
Predicted Functional Partners:
K4AH90_SETIT
Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
   
 0.965
K3YRI2_SETIT
Protein kinase domain-containing protein.
   
 0.943
A0A368SW23
Cyclin-dependent kinase inhibitor; Belongs to the CDI family. ICK/KRP subfamily.
    
 
 0.919
K4A036_SETIT
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.909
A0A368PYQ0
CYCLIN domain-containing protein; Belongs to the cyclin family.
   
 0.903
K3Z445_SETIT
DNA helicase; Belongs to the MCM family.
   
 0.903
A0A0Q3NDR4
Uncharacterized protein.
    
 
 0.873
A0A0Q3QYX0
Uncharacterized protein.
    
 
 0.873
K4ABB6_SETIT
Uncharacterized protein.
   
 0.867
K3XEG9_SETIT
DNA helicase; Belongs to the MCM family.
   
 0.855
Your Current Organism:
Setaria italica
NCBI taxonomy Id: 4555
Other names: Chaetochloa italica, Chaetochloa italica (L.) Scribn., Panicum italicum, Panicum italicum L., S. italica, Setaria italica (L.) P.Beauv., Setaria viridis subsp. italica, Setaria viridis subsp. italica (L.) Briq., foxtail millet
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