STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypBHydrogenase expression/formation protein HypB. (242 aa)    
Predicted Functional Partners:
hypD
Hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
  
 0.989
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.987
hypC
Hydrogenase expression/formation protein HypC.
 
  
 0.986
hypE
Hydrogenase expression/formation protein HypE.
 
  
 0.969
hypF
Hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.968
Ljor_1606
(2R)-phospho-3-sulfolactate synthase (ComA).
  
    0.856
vhtD
Hydrogenase expression/formation protein.
 
  
 0.843
Ljor_0027
Hydrogenase subunit.
     
 0.777
HoxY
Sulfhydrogenase subunit delta.
     
 0.777
HoxH
Coenzyme F420-reducing hydrogenase, alpha subunit.
     
 0.777
Your Current Organism:
Legionella jordanis
NCBI taxonomy Id: 456
Other names: ATCC 33623, CCUG 16413, CIP 105268, DSM 19212, L. jordanis, NCTC 11533, strain BL 540, strain BL-540
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.