STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B9G98_01955Topoisomerase 1-associated factor 1. (972 aa)    
Predicted Functional Partners:
B9G98_04450
Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family.
   
 0.996
B9G98_03883
DNA helicase; Belongs to the MCM family.
   
 
 0.985
B9G98_00687
Cell division control protein 45.
   
 
 0.968
B9G98_02158
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
   
 
 0.968
B9G98_04099
Minichromosome loss protein 1.
   
 
 0.964
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.960
B9G98_00602
DNA helicase; Belongs to the MCM family.
   
 
 0.958
B9G98_01253
DNA helicase; Belongs to the MCM family.
   
 
 0.954
B9G98_02793
DNA helicase; Belongs to the MCM family.
   
 
 0.950
B9G98_04727
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
 
 0.945
Your Current Organism:
Wickerhamiella sorbophila
NCBI taxonomy Id: 45607
Other names: AJ 4995, ATCC 60130, CBS 6739, CCRC 22618, CCRC:22618, Candida sorbophila, NRRL Y-7921, Torulopsis sorbophila, W. sorbophila
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