B9G98_02380 protein (Wickerhamiella sorbophila)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

B9G98_02380

Trehalose-6-phosphate synthase. (481 aa)

Predicted Functional Partners:

B9G98_02295

0.993

B9G98_02110

0.930

B9G98_04253

0.877

B9G98_04167

0.869

B9G98_00245

0.850

B9G98_00375

0.809

B9G98_03117

0.640

B9G98_00725

0.632

B9G98_01280

0.632

B9G98_02189

0.608

Your Current Organism:

Wickerhamiella sorbophila

NCBI taxonomy Id: 45607
Other names: AJ 4995, ATCC 60130, CBS 6739, CCRC 22618, CCRC:22618, Candida sorbophila, NRRL Y-7921, Torulopsis sorbophila, W. sorbophila

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B9G98_00245	B9G98_00375	A0A2T0FCD5	A0A2T0FCR2	Glycogenin-1.	1,4-alpha-glucan-branching enzyme.	0.998
B9G98_00245	B9G98_02295	A0A2T0FCD5	A0A2T0FI70	Glycogenin-1.	Trehalose-phosphatase.	0.791
B9G98_00245	B9G98_02380	A0A2T0FCD5	A0A2T0FIE3	Glycogenin-1.	Trehalose-6-phosphate synthase.	0.850
B9G98_00245	B9G98_03117	A0A2T0FCD5	A0A2T0FKK5	Glycogenin-1.	Phosphoglucomutase; Belongs to the phosphohexose mutase family.	0.481
B9G98_00245	B9G98_04167	A0A2T0FCD5	A0A2T0FNJ0	Glycogenin-1.	UTP--glucose-1-phosphate uridylyltransferase.	0.839
B9G98_00245	B9G98_04253	A0A2T0FCD5	A0A2T0FNR6	Glycogenin-1.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.999
B9G98_00375	B9G98_00245	A0A2T0FCR2	A0A2T0FCD5	1,4-alpha-glucan-branching enzyme.	Glycogenin-1.	0.998
B9G98_00375	B9G98_02110	A0A2T0FCR2	A0A2T0FHM6	1,4-alpha-glucan-branching enzyme.	Trehalase.	0.893
B9G98_00375	B9G98_02295	A0A2T0FCR2	A0A2T0FI70	1,4-alpha-glucan-branching enzyme.	Trehalose-phosphatase.	0.791
B9G98_00375	B9G98_02380	A0A2T0FCR2	A0A2T0FIE3	1,4-alpha-glucan-branching enzyme.	Trehalose-6-phosphate synthase.	0.809
B9G98_00375	B9G98_03117	A0A2T0FCR2	A0A2T0FKK5	1,4-alpha-glucan-branching enzyme.	Phosphoglucomutase; Belongs to the phosphohexose mutase family.	0.986
B9G98_00375	B9G98_04167	A0A2T0FCR2	A0A2T0FNJ0	1,4-alpha-glucan-branching enzyme.	UTP--glucose-1-phosphate uridylyltransferase.	0.753
B9G98_00375	B9G98_04253	A0A2T0FCR2	A0A2T0FNR6	1,4-alpha-glucan-branching enzyme.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.999
B9G98_00725	B9G98_02295	A0A2T0FDR6	A0A2T0FI70	1,3-beta-glucan synthase component FKS1.	Trehalose-phosphatase.	0.627
B9G98_00725	B9G98_02380	A0A2T0FDR6	A0A2T0FIE3	1,3-beta-glucan synthase component FKS1.	Trehalose-6-phosphate synthase.	0.632
B9G98_00725	B9G98_04167	A0A2T0FDR6	A0A2T0FNJ0	1,3-beta-glucan synthase component FKS1.	UTP--glucose-1-phosphate uridylyltransferase.	0.649
B9G98_00725	B9G98_04253	A0A2T0FDR6	A0A2T0FNR6	1,3-beta-glucan synthase component FKS1.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.646
B9G98_01280	B9G98_02295	A0A2T0FFA8	A0A2T0FI70	1,3-beta-glucan synthase component FKS1.	Trehalose-phosphatase.	0.627
B9G98_01280	B9G98_02380	A0A2T0FFA8	A0A2T0FIE3	1,3-beta-glucan synthase component FKS1.	Trehalose-6-phosphate synthase.	0.632
B9G98_01280	B9G98_04167	A0A2T0FFA8	A0A2T0FNJ0	1,3-beta-glucan synthase component FKS1.	UTP--glucose-1-phosphate uridylyltransferase.	0.649

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

12

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009168

Purine ribonucleoside monophosphate biosynthetic process

10 of 16

2.96

12.45

5.84e-25

GO:0006189

De novo IMP biosynthetic process

8 of 8

3.17

10.77

6.83e-21

GO:0009152

Purine ribonucleotide biosynthetic process

10 of 75

2.29

8.19

3.43e-20

GO:0006144

Purine nucleobase metabolic process

5 of 19

2.59

5.02

1.82e-10

GO:0009113

Purine nucleobase biosynthetic process

4 of 9

2.81

4.39

6.59e-09

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016879

Ligase activity, forming carbon-nitrogen bonds

4 of 57

2.01

2.0

9.05e-05

GO:0016742

Hydroxymethyl-, formyl- and related transferase activity

2 of 7

2.62

1.24

0.0054

GO:0016763

Pentosyltransferase activity

2 of 23

2.11

0.96

0.0159

GO:0046872

Metal ion binding

7 of 1500

0.84

0.61

0.0054

GO:0032555

Purine ribonucleotide binding

6 of 1223

0.86

0.56

0.0138

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 4945

0.51

0.41

0.0018

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:12556

De novo IMP biosynthetic process

10 of 10

3.17

13.83

5.88e-27

CL:12554

Purine nucleoside monophosphate metabolic process, and Purine-containing compound catabolic process

11 of 27

2.78

12.84

4.74e-27

CL:12559

De novo IMP biosynthetic process

5 of 5

3.17

6.34

2.23e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

10 of 118

2.1

6.81

1.07e-18

map00250

Alanine, aspartate and glutamate metabolism

3 of 44

2.0

1.91

0.00014

map01110

Biosynthesis of secondary metabolites

8 of 615

1.28

1.81

5.03e-08

map00670

One carbon pool by folate

2 of 24

2.09

1.26

0.0039

map01100

Metabolic pathways

10 of 2204

0.82

0.85

1.06e-06

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-73817

Purine ribonucleoside monophosphate biosynthesis

9 of 12

3.04

11.59

7.36e-23

MAP-8956320

Nucleotide biosynthesis

9 of 18

2.87

10.82

5.87e-22

MAP-15869

Metabolism of nucleotides

10 of 67

2.34

8.57

1.13e-20

MAP-1430728

Metabolism

10 of 1495

0.99

1.17

1.13e-07

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0658

Purine biosynthesis

3 of 5

2.95

3.0

3.22e-06

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02769

AIR synthase related protein, C-terminal domain

2 of 2

3.17

1.41

0.0029

PF00156

Phosphoribosyl transferase domain

2 of 4

2.87

1.34

0.0037

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036921

PurM-like, N-terminal domain superfamily

2 of 2

3.17

1.15

0.0085

IPR036676

PurM-like, C-terminal domain superfamily

2 of 2

3.17

1.15

0.0085

IPR010918

PurM-like, C-terminal domain

2 of 2

3.17

1.15

0.0085

IPR013815

ATP-grasp fold, subdomain 1

2 of 9

2.51

0.94

0.0194

IPR011054

Rudiment single hybrid motif

2 of 9

2.51

0.94

0.0194

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (18%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About