STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mvol_1118KEGG: bpy:Bphyt_4256 NADPH-dependent F420 reductase; TIGRFAM: NADPH-dependent F420 reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein. (231 aa)    
Predicted Functional Partners:
Mvol_0888
F420-dependent oxidoreductase; KEGG: eba:p2A347 hypothetical protein; TIGRFAM: F420-dependent oxidoreductase; PFAM: protein of unknown function DUF129.
 
   
 0.792
cofD
LPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.780
cofC
2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
 
   
 0.744
mer
5,10-methylenetetrahydromethanopterin reductase; Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT; Belongs to the mer family.
 
  
 0.739
cofG
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
 
   
 0.698
Mvol_1119
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: gur:Gura_4159 xylose isomerase domain-containing protein.
  
    0.578
Mvol_1117
Hypothetical protein.
       0.541
cofH
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit; Catalyzes the radical-mediated synthesis of 5-amino-5-(4- hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil from 5-amino-6-(D- ribitylamino)uracil and L-tyrosine.
 
   
 0.470
Your Current Organism:
Methanococcus voltae
NCBI taxonomy Id: 456320
Other names: M. voltae A3, Methanococcus voltae A3, Methanococcus voltae str. A3, Methanococcus voltae strain A3
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