node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mvol_0109 | queC | Mvol_0109 | Mvol_1466 | KEGG: spl:Spea_2230 CrcB protein; TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.645 |
Mvol_0351 | queC | Mvol_0351 | Mvol_1466 | KEGG: hypothetical protein; K01737 6-pyruvoyl tetrahydrobiopterin synthase. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.991 |
Mvol_0351 | queE | Mvol_0351 | Mvol_1433 | KEGG: hypothetical protein; K01737 6-pyruvoyl tetrahydrobiopterin synthase. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.998 |
Mvol_0351 | tgtA | Mvol_0351 | Mvol_0802 | KEGG: hypothetical protein; K01737 6-pyruvoyl tetrahydrobiopterin synthase. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.829 |
Mvol_0351 | tmk | Mvol_0351 | Mvol_1015 | KEGG: hypothetical protein; K01737 6-pyruvoyl tetrahydrobiopterin synthase. | TIGRFAM: thymidylate kinase; KEGG: scl:sce0834 putative thymidylate kinase; PFAM: thymidylate kinase. | 0.687 |
Mvol_1325 | queC | Mvol_1325 | Mvol_1466 | PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; KEGG: pnu:Pnuc_0770 tRNA pseudouridine synthase A. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.657 |
Mvol_1325 | tgtA | Mvol_1325 | Mvol_0802 | PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; KEGG: pnu:Pnuc_0770 tRNA pseudouridine synthase A. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.492 |
Mvol_1325 | tmk | Mvol_1325 | Mvol_1015 | PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; KEGG: pnu:Pnuc_0770 tRNA pseudouridine synthase A. | TIGRFAM: thymidylate kinase; KEGG: scl:sce0834 putative thymidylate kinase; PFAM: thymidylate kinase. | 0.467 |
Mvol_1325 | trm1 | Mvol_1325 | Mvol_1468 | PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; KEGG: pnu:Pnuc_0770 tRNA pseudouridine synthase A. | N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.694 |
cofC | queC | Mvol_1513 | Mvol_1466 | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.668 |
cofC | queE | Mvol_1513 | Mvol_1433 | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.571 |
crcB | queC | Mvol_0049 | Mvol_1466 | CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.645 |
queC | Mvol_0109 | Mvol_1466 | Mvol_0109 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | KEGG: spl:Spea_2230 CrcB protein; TIGRFAM: CrcB protein; PFAM: Camphor resistance CrcB protein. | 0.645 |
queC | Mvol_0351 | Mvol_1466 | Mvol_0351 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | KEGG: hypothetical protein; K01737 6-pyruvoyl tetrahydrobiopterin synthase. | 0.991 |
queC | Mvol_1325 | Mvol_1466 | Mvol_1325 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; KEGG: pnu:Pnuc_0770 tRNA pseudouridine synthase A. | 0.657 |
queC | cofC | Mvol_1466 | Mvol_1513 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. | 0.668 |
queC | crcB | Mvol_1466 | Mvol_0049 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | CrcB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | 0.645 |
queC | queE | Mvol_1466 | Mvol_1433 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.999 |
queC | tgtA | Mvol_1466 | Mvol_0802 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Archaeosine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.848 |
queC | tiaS | Mvol_1466 | Mvol_0248 | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Domain of unknown function DUF1743; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.620 |