STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (328 aa)    
Predicted Functional Partners:
APO91175.1
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.998
maeB
NADP-dependent malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.988
gltA
Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family.
  
 0.986
aspA
Aspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.975
icd
Isocitrate dehydrogenase (NADP(+)); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family.
  
  
 0.958
APO92264.1
Malate synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.937
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.928
gltB
Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.912
acnB
Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family.
  
  
 0.879
gapA
Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.875
Your Current Organism:
Xanthomonas euvesicatoria
NCBI taxonomy Id: 456327
Other names: ATCC 11633, Bacterium vesicatorium, DSM 19128, ICMP 109, ICMP 98, NCPPB 2968, X. euvesicatoria, Xanthomonas campestris (pv. vesicatoria), Xanthomonas campestris pv. Vesicatoria type A, Xanthomonas campestris pv. vesicatoria, Xanthomonas euvesicatoria Jones et al. 2006 emend. Constantin et al. 2016
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.