STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXT71389.1ABC transporter ATP-binding protein uup. (540 aa)    
Predicted Functional Partners:
rplD
LSU ribosomal protein L4p (L1e); Forms part of the polypeptide exit tunnel.
   
 
 0.748
rpsE
SSU ribosomal protein S5p (S2e); Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
  
   0.746
rplU
LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
   0.743
rplM
LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.742
rpsO
SSU ribosomal protein S15p (S13e); Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
   0.741
rpsC
SSU ribosomal protein S3p (S3e); Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
   
   0.741
rplC
LSU ribosomal protein L3p (L3e); One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.728
rpmH
LSU ribosomal protein L34p; Belongs to the bacterial ribosomal protein bL34 family.
   
   0.724
rplR
LSU ribosomal protein L18p (L5e); This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
   
   0.724
rpmF
LSU ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family.
   
   0.722
Your Current Organism:
Streptococcus cristatus
NCBI taxonomy Id: 45634
Other names: AS 1.3089 [[Streptococcus oligofermentans]], ATCC 51100, CCUG 33481, CCUG 48365 [[Streptococcus oligofermentans]], CCUG 58097 [[Streptococcus oligofermentans]], CGMCC 1.3089 [[Streptococcus oligofermentans]], CIP 105954, CIP 108229 [[Streptococcus oligofermentans]], DSM 19165 [[Streptococcus oligofermentans]], DSM 8249, LMG 16320, LMG 21535 [[Streptococcus oligofermentans]], LMG 22279 [[Streptococcus oligofermentans]], LMG:16320, LMG:21535 [[Streptococcus oligofermentans]], LMG:22279 [[Streptococcus oligofermentans]], NCTC 12479, S. cristatus, Streptococcus crista, Streptococcus oligofermentans, Streptococcus oligofermentans Tong et al. 2003, strain CR311
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