STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KXT70222.1Accessory secretory protein Asp2. (519 aa)    
Predicted Functional Partners:
KXT70221.1
Accessory secretory protein Asp1.
 
 
 
 0.990
KXT70223.1
Accessory secretory protein Asp3.
 
 
 
 0.978
gtfA
Poly(glycerol-phosphate) alpha-glucosyltransferase GftA; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. Catalyzes the first step in glycosylation by transferring N-acetylglucosamine from UDP-GlcNAc to serine residues in the substrate protein. Part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon.
 
 
 
 0.939
gtfB
Hypothetical protein; Required for polymorphic O-glycosylation of the serine-rich repeat protein in this bacteria. A stabilizing protein that is part of the accessory SecA2/SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. The GtfA-GtfB complex adds GlcNAc from UDP-GlcNAc to the substrate protein, attaching the first sugar residue. Stabilizes the glycosylation activity of GtfA. Has no N-acetylglucosaminyl transferase activity on its own.
 
 
 
 0.939
secY2
Preprotein translocase secY subunit; Part of the accessory SecA2/SecY2 system specifically required for export of possible cell wall proteins. The central subunit of a protein translocation channel.
 
   
 0.847
KXT70118.1
Glycosyltransferase LafB, responsible for the formation of Gal-Glc-DAG.
   
 
 0.720
KXT69926.1
Glycosyltransferase.
   
 
 0.720
KXT69924.1
Lipopolysaccharide biosynthesis protein.
   
 
 0.717
KXT69927.1
Alpha-D-GlcNAc alpha-1,2-L-rhamnosyltransferase.
   
 
 0.717
KXT70219.1
Glycosyl transferase, family 8.
 
     0.672
Your Current Organism:
Streptococcus cristatus
NCBI taxonomy Id: 45634
Other names: AS 1.3089 [[Streptococcus oligofermentans]], ATCC 51100, CCUG 33481, CCUG 48365 [[Streptococcus oligofermentans]], CCUG 58097 [[Streptococcus oligofermentans]], CGMCC 1.3089 [[Streptococcus oligofermentans]], CIP 105954, CIP 108229 [[Streptococcus oligofermentans]], DSM 19165 [[Streptococcus oligofermentans]], DSM 8249, LMG 16320, LMG 21535 [[Streptococcus oligofermentans]], LMG 22279 [[Streptococcus oligofermentans]], LMG:16320, LMG:21535 [[Streptococcus oligofermentans]], LMG:22279 [[Streptococcus oligofermentans]], NCTC 12479, S. cristatus, Streptococcus crista, Streptococcus oligofermentans, Streptococcus oligofermentans Tong et al. 2003, strain CR311
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