STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acpP_1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (80 aa)    
Predicted Functional Partners:
acpP_2
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
  
  
  0.916
fabD
Malonyl CoA-acyl carrier protein transacylase.
  
 0.896
KXT71417.1
D-alanyl transfer protein DltB; Could be involved in the transport of activated D-alanine through the membrane.
  
 
 0.885
acpS
Holo-(acyl-carrier protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
  
 
 0.871
dltA
D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...]
  
 
 0.863
rpmF
LSU ribosomal protein L32p; Belongs to the bacterial ribosomal protein bL32 family.
  
 
 0.860
KXT70695.1
3-oxoacyl-(acyl-carrier-protein) synthase, KASII; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
  
 
 0.855
rplU
LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.854
rplT
LSU ribosomal protein L20p; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
 
 0.842
rplM
LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
   0.841
Your Current Organism:
Streptococcus cristatus
NCBI taxonomy Id: 45634
Other names: AS 1.3089 [[Streptococcus oligofermentans]], ATCC 51100, CCUG 33481, CCUG 48365 [[Streptococcus oligofermentans]], CCUG 58097 [[Streptococcus oligofermentans]], CGMCC 1.3089 [[Streptococcus oligofermentans]], CIP 105954, CIP 108229 [[Streptococcus oligofermentans]], DSM 19165 [[Streptococcus oligofermentans]], DSM 8249, LMG 16320, LMG 21535 [[Streptococcus oligofermentans]], LMG 22279 [[Streptococcus oligofermentans]], LMG:16320, LMG:21535 [[Streptococcus oligofermentans]], LMG:22279 [[Streptococcus oligofermentans]], NCTC 12479, S. cristatus, Streptococcus crista, Streptococcus oligofermentans, Streptococcus oligofermentans Tong et al. 2003, strain CR311
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