STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_0157TIGRFAM: putative hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase, N-terminal domain; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; KEGG: mhu:Mhun_0151 hydroxymethylglutaryl-CoA synthase, putative; Belongs to the thiolase-like superfamily. UPF0219 family. (350 aa)    
Predicted Functional Partners:
Mboo_0137
KEGG: mhu:Mhun_3004 3-hydroxy-3-methylglutaryl coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase; PFAM: hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
 
 0.999
Mboo_0155
PFAM: protein of unknown function DUF35; KEGG: mac:MA4043 hypothetical protein.
 
 
 0.999
Mboo_0156
PFAM: Thiolase; KEGG: mhu:Mhun_0150 thiolase.
 
 0.999
Mboo_0158
SMART: helix-turn-helix domain protein; KEGG: mhu:Mhun_0152 transcriptional regulator, XRE family.
 
    0.973
Mboo_0172
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: sat:SYN_00693 pyruvate synthase gamma chain.
    
 0.915
Mboo_0203
TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: mhu:Mhun_2394 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate.
    
 0.915
Mboo_0675
KEGG: mhu:Mhun_0450 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase.
    
 0.915
Mboo_0170
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: sat:SYN_00691 pyruvate synthase subunit.
    
 0.906
Mboo_0205
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: sat:SYN_00691 pyruvate synthase subunit.
    
 0.906
Mboo_0672
PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; KEGG: mhu:Mhun_0453 thiamine pyrophosphate enzyme-like TPP-binding.
    
 0.906
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.