STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_0181PFAM: protein of unknown function DUF105; cysteine-rich small domain; KEGG: mhu:Mhun_2543 protein of unknown function DUF105. (296 aa)    
Predicted Functional Partners:
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.994
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
    
  0.975
cobS
Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
   
 0.842
Mboo_0703
PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: mhu:Mhun_1589 protein of unknown function DUF102; Belongs to the UPF0284 family.
 
   
 0.842
Mboo_1226
TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0995 precorrin-3B C17-methyltransferase.
     
 0.803
Mboo_0983
PFAM: periplasmic binding protein; KEGG: mhu:Mhun_0260 periplasmic binding protein.
 
  
 0.795
cbiD
Cobalamin (vitamin B12) biosynthesis CbiD protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
     
 0.791
Mboo_0182
KEGG: mhu:Mhun_2544 oxygen-sensitive ribonucleoside-triphosphate reductase-like.
       0.782
Mboo_1227
PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: mhu:Mhun_3212 cobalamin (vitamin B12) biosynthesis CbiG protein.
     
 0.779
Mboo_1407
KEGG: mhu:Mhun_0939 5-deoxyadenosylcobinamide phosphate nucleotidyltransferase.
 
     0.774
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.