STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_0210KEGG: mhu:Mhun_2403 hypothetical protein. (123 aa)    
Predicted Functional Partners:
rpl40e
PFAM: Ribosomal protein L40e; KEGG: mhu:Mhun_2870 ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 0.991
Mboo_1951
PFAM: RNA binding S1 domain protein; translation initiation factor 2, alpha subunit; KEGG: mhu:Mhun_1128 translation initiation factor 2, alpha subunit.
  
 0.988
Mboo_1458
KEGG: mhu:Mhun_1040 26S proteasome subunit P45 family; TIGRFAM: 26S proteasome subunit P45 family; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; Belongs to the AAA ATPase family.
  
 0.968
pan
26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...]
  
 0.968
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 0.953
eif2b
Putative translation initiation factor aIF-2, beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
 
 0.952
rps19
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 0.950
rps15
PFAM: ribosomal protein S15; Ribosomal S13S15-like; KEGG: mhu:Mhun_2511 ribosomal S13S15-like.
  
 0.945
rps2
PFAM: ribosomal protein S2; KEGG: mhu:Mhun_2892 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
 
 0.942
rps24e
KEGG: mma:MM0599 SSU ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 0.940
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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