STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_0505PFAM: DNA methylase N-4/N-6 domain protein; KEGG: mhu:Mhun_2937 DNA methylase N-4/N-6. (239 aa)    
Predicted Functional Partners:
Mboo_0503
Thiamine pyrophosphate enzyme domain protein TPP-binding; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
       0.777
Mboo_0504
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; KEGG: mhu:Mhun_2359 pyruvate ferredoxin/flavodoxin oxidoreductase.
       0.777
Mboo_1003
DNA adenine methylase; KEGG: gvi:glr2709 site-specific DNA-methyltransferase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase.
 
  
 0.506
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
    0.478
Mboo_0727
KEGG: mhu:Mhun_0095 succinyl-CoA synthetase, beta subunit; TIGRFAM: succinyl-CoA synthetase, beta subunit; PFAM: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp domain protein.
  
    0.478
Mboo_0502
KEGG: mhu:Mhun_2356 hypothetical protein.
       0.404
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.