STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mboo_0585PFAM: Methyl-coenzyme M reductase, protein D; KEGG: mhu:Mhun_2145 methyl-coenzyme M reductase, protein D. (156 aa)    
Predicted Functional Partners:
Mboo_0582
Coenzyme-B sulfoethylthiotransferase; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
  
 
 0.997
Mboo_0583
PFAM: Methyl-coenzyme M reductase, gamma subunit; KEGG: mhu:Mhun_2147 methyl-coenzyme M reductase, gamma subunit.
  
 
 0.997
Mboo_0584
PFAM: Methyl-coenzyme M reductase operon protein C; KEGG: mhu:Mhun_2146 methyl-coenzyme M reductase operon protein C.
  
 
 0.997
Mboo_0586
PFAM: Methyl-coenzyme M reductase, beta subunit; KEGG: mhu:Mhun_2144 methyl-coenzyme M reductase, beta subunit.
  
 
 0.997
Mboo_2434
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mhu:Mhun_2311 ABC transporter related.
    
 0.926
mtrA-2
Tetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
  
 
 0.816
Mboo_0588
4Fe-4S ferredoxin, iron-sulfur binding domain protein; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
  
 
 0.814
mtrE
Tetrahydromethanopterin S-methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
 
 0.807
mtrD
Tetrahydromethanopterin S-methyltransferase, subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
 
  0.789
mtrB
Tetrahydromethanopterin S-methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
 
  0.784
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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