STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (236 aa)    
Predicted Functional Partners:
Mboo_1407
KEGG: mhu:Mhun_0939 5-deoxyadenosylcobinamide phosphate nucleotidyltransferase.
 
  
 0.968
Mboo_1226
TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mma:MM0995 precorrin-3B C17-methyltransferase.
 
  
 0.930
Mboo_0703
PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: mhu:Mhun_1589 protein of unknown function DUF102; Belongs to the UPF0284 family.
 
  
 0.927
Mboo_0702
PFAM: phosphatidylglycerophosphatase A; KEGG: pho:PH0374 hypothetical protein.
    
  0.915
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.866
Mboo_0181
PFAM: protein of unknown function DUF105; cysteine-rich small domain; KEGG: mhu:Mhun_2543 protein of unknown function DUF105.
 
   
 0.842
Mboo_1229
PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mhu:Mhun_3210 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.835
Mboo_1225
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: mhu:Mhun_3214 precorrin-8X methylmutase CbiC/CobH.
 
  
 0.797
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
  
 0.792
Mboo_1228
PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mhu:Mhun_3211 precorrin-4 C11-methyltransferase.
  
  
 0.753
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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