STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (310 aa)    
Predicted Functional Partners:
Mboo_2060
KEGG: mhu:Mhun_0564 hypothetical protein.
   
 
 0.913
Mboo_1513
PFAM: oxidoreductase domain protein; Oxidoreductase, C-terminal domain; KEGG: mag:amb0132 predicted dehydrogenase and related protein.
  
 
 0.617
Mboo_1833
PFAM: oxidoreductase domain protein; CoA-binding domain protein; KEGG: mhu:Mhun_2141 oxidoreductase-like.
  
 
 0.617
Mboo_0708
PFAM: amino acid-binding ACT domain protein; KEGG: mhu:Mhun_1623 amino acid-binding ACT.
 
     0.549
Mboo_0709
KEGG: mhu:Mhun_1624 phenylacetate--CoA ligase.
       0.489
Mboo_0710
KEGG: mhu:Mhun_1625 phenylacetate--CoA ligase.
       0.489
Mboo_1656
TIGRFAM: transposase, IS605 OrfB family; PFAM: transposase, IS605 OrfB; KEGG: mma:MM0579 transposase.
 
     0.476
argF
KEGG: mba:Mbar_A3512 ornithine carbamoyltransferase; TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain.
   
    0.408
Mboo_1745
PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: mhu:Mhun_3155 short-chain dehydrogenase/reductase SDR.
 
    0.408
Mboo_0111
TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; KEGG: mhu:Mhun_0890 crossover junction endodeoxyribonuclease RuvC.
     
 0.407
Your Current Organism:
Methanoregula boonei
NCBI taxonomy Id: 456442
Other names: Candidatus Methanoregula boonei 6A8, M. boonei 6A8, Methanoregula boonei 6A8, Methanoregula boonei str. 6A8, Methanoregula boonei strain 6A8, methanogenic archaeon 6A8
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